Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p052 | (1) | SRF2015

The effect of reproductive ageing on chromatin configuration and amino acid metabolism in germinal vesicle staged sheep oocytes in vitro

Topipat Chutima , Lu Jianping , Fernandez Esther Collado , Huntriss John , Picton Helen

Reproductive ageing in females is associated with reduced oocyte maturation potential and developmental competence. Oocyte chromatin configuration and metabolism, have recently been established as correlates of oocyte developmental competence in a number of species. Here, we have evaluated the effect of reproductive ageing on oocyte chromatin morphology and amino acid turnover in germinal vesicle (GV)-staged, ovine oocytes.Cumulus–oocyte complexes w...